Follicular variant of peripheral T-cell lymphoma

Follicular variant of peripheral T-cell lymphoma

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Globally, peripheral T-cell lymphomas (PTCLs) constitute about 12% of all non-Hodgkin lymphomas, of which the unspecified category is the most common subtype (30%).Mostly, the unspecified category shows a diffuse pattern of involvement in the lymph nodes.However, rarely, they may show a follicular/nodular pattern mimicking a follicular lymphoma.

We report a case of a follicular variant of ps5 price new jersey PTCL, not otherwise specified.This case displayed a striking nodular/follicular pattern with an admixture of small (centrocyte-like) and large (centroblast-like) cells, thus mimicking a follicular lymphoma.The neoplastic cells were strongly positive for both CD3 and CD20.

In addition, they were positive for pan T-cell markers and PD-1.T-cell receptor gene rearrangement studies highlighted a monoclonal T-cell population.Even though this variant of PTCL is very rare, it is important to keep it as a differential la rams crop top for the lymphomas exhibiting nodular pattern.